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1

Semisynthetic Chemical Modification of the Antifungal Lipopeptide Echinocandin B (ECB): Structure-Activity Studies of the Lipophilic and Geometric Parameters of Polyarylated Acyl Analogs of ECB

Debono, Manuel, Turner, William W., LaGrandeur, Lisa, Burkhardt, Fred J., Nissen, Jeffrey S., Nichols, Kimberly K., Rodriguez, Michael J., Zweifel, Mark J., Zeckner, Douglas J.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.46 MB

english, 1995

2

The structures of A10255 B, -G and -J: new thiopeptide antibiotics produced by Streptomyces gardneri

Debono, Manuel, Molloy, R. Michael, Occolowitz, John L., Paschal, Jonathan W., Hunt, Ann H., Michel, Karl H., Martin, James W.

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 1.02 MB

english, 1992

3

Actaplanin, new glycopeptide antibiotics produced by Actinoplanes missouriensis. The isolation and preliminary chemical characterization of actaplanin.

DEBONO, MANUEL, MERKEL, KURT E., MOLLOY, R. MICHAEL, BARNHART, MITCHELL, PRESTI, EUGENE, HUNT, ANN H., HAMILL, ROBERT L.

Journal:

The Journal of Antibiotics

Year:

1984

Language:

english

File:

PDF, 5.75 MB

english, 1984

4

Polyether Antibiotics, Volume 2: Naturally Occurring Acid Ionophores. Edited by John W. Wesley. Marcel Dekker, 270 Madison Avenue, New York, NY 10016. 1983. 415 pp. 15 × 23 cm. Price $65.00 (20% higher outside the U.S. And Canada)

Journal:

Journal of Pharmaceutical Sciences

Year:

1984

Language:

english

File:

PDF, 167 KB

english, 1984

5

Tjipanazoles, new antifungal agents from the blue-green alga Tolypothrix tjipanasensis

Rosanne Bonjouklian, Tim A. Smitka, Larry E. Doolin, R.Michael Molloy, Manuel Debono, Stacey A. Shaffer, Richard E. Moore, Jeffrey B. Stewart, Gregory M.L. Patterson

Journal:

Year:

1991

Language:

english

File:

PDF, 855 KB

english, 1991

6

Isolation and characterization of 4-epi-vancosamine

Ann H. Hunt, R.Michael Molloy, Manuel Debono, John L. Occolowitz

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 177 KB

english, 1988

7

Photochemical lactolization and deconjugation of trans-steroidal .alpha.,.beta. unsaturated acids

Debono, Manuel., Molloy, R. Michael.

Journal:

Journal of Organic Chemistry

Year:

1970

Language:

english

File:

PDF, 574 KB

english, 1970

8

New compounds and improved procedures: A convenient synthesis of 11β, 17β-dihydroxy-ESTR-4,9(10)-dien-3-one

Manuel Debono, R.M. Molloy

Journal:

Year:

1969

Language:

english

File:

PDF, 208 KB

english, 1969

9

The photodimerization of 17β-hydroxy-estra-4,9(10)-dien-3-one

Journal:

Year:

1968

Language:

english

File:

PDF, 151 KB

english, 1968

10

Anti-Candida Activity and Toxicology of LY121019, a Novel Semisynthetic Polypeptide Antifungal Antibiotic

ROBERT S. GORDEE, DOUGLAS J. ZECKNER, LEONARD C. HOWARD, WILLIAM E. ALBORN JR., MANUEL DEBONO

Journal:

Annals of the New York Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 595 KB

english, 1988

11

Synthesis and characterization of halogenated derivatives of the ionophore of 5-(methylamino)-2-[[3,9,11-trimethyl-8-[1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid: enhanced calcium ion transport specificity by the 4-bromo derivative

Debono, Manuel, Molloy, R. M., Dorman, D. E., Paschal, J. W., Babcock, Donner F., Deber, Charles M., Pfeiffer, Douglas R.

Journal:

Year:

1981

Language:

english

File:

PDF, 1.06 MB

english, 1981

12

Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics

Kirst, Herbert A., Toth, John E., Debono, Manuel, Willard, Kevin E., Truedell, Brenda A., Ott, John L., Counter, Fred T., Felty-Duckworth, Anna M., Pekarek, Robert S.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 1.45 MB

english, 1988

13

Condensation of glyoxylic acid with 5.alpha.-androstanolone

Debono, Manuel, Molloy, R. Michael, Patterson, L. E.

Journal:

Journal of Organic Chemistry

Year:

1969

Language:

english

File:

PDF, 524 KB

english, 1969

14

Studies of Terpene Chemistry. I. The Acid-Catalyzed Dimerization of Citronellal 1

Dolby, Lloyd J., Debono, Manuel

Journal:

Journal of Organic Chemistry

Year:

1964

Language:

english

File:

PDF, 683 KB

english, 1964

15

Structure of the major glycopeptide of the teicoplanin complex

Hunt, Ann H., Molloy, R. Michael, Occolowitz, John L., Marconi, Gary G., Debono, Manuel

Journal:

Journal of the American Chemical Society

Year:

1984

Language:

english

File:

PDF, 636 KB

english, 1984

16

Lead tetraacetate oxidation of steroidal hydrazones

Debono, Manuel, Molloy, R. Michael

Journal:

Journal of Organic Chemistry

Year:

1969

Language:

english

File:

PDF, 248 KB

english, 1969

17

Photolysis of 9α,10α- and 9β,10β-Oxidoestr-4-en-3-ones

Debono, Manuel., Molloy, R. Michael., Bauer, Daniel., Iizuka, Takeshi., Schaffner, Kurt., Jeger, Oskar.

Journal:

Journal of the American Chemical Society

Year:

1970

Language:

english

File:

PDF, 371 KB

english, 1970

18

Chemistry of 10.alpha.-estr-4-en-17.beta.-ol-3-one and selected transformation products

Debono, Manuel, Farkas, Eugene, Molloy, R. Michael, Owen, John M.

Journal:

Journal of Organic Chemistry

Year:

1969

Language:

english

File:

PDF, 569 KB

english, 1969

19

Biotransformation of Vancomycin B to Vancomycin Hexapeptide by a Soil Microorganism

Zmijewski, Milton J., Logan, Robert M., Marconi, Gary, Debono, Manuel, Molloy, R. Michael, Chadwell, Fred, Briggs, Barbara

Journal:

Journal of Natural Products

Year:

1989

Language:

english

File:

PDF, 247 KB

english, 1989

20

Ring B functionalization of the 10.alpha.-estr-4-en-17.beta.-ol-3-one system

Debono, Manuel, Molloy, R. Michael

Journal:

Journal of Organic Chemistry

Year:

1969

Language:

english

File:

PDF, 384 KB

english, 1969

21

Structures of the actaplanins

Hunt, Ann H., Elzey, Thomas K., Merkel, Kurt E., Debono, Manuel

Journal:

Journal of Organic Chemistry

Year:

1984

Language:

english

File:

PDF, 631 KB

english, 1984

22

Synthesis and structure-activity relationships of new 9-N-alkyl derivatives of 9(S)-erythromycylamine

Kirst, Herbert A., Wind, Julie A., Leeds, James P., Willard, Kevin E., Debono, Manuel, Bonjouklian, Rosanne, Greene, James M., Sullivan, Kevin A., Paschal, Jonathan W.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1.23 MB

english, 1990

23

The structures of A10255 B, -G, and -J: new thiopeptide antibiotics produced by Streptomyces gardneri. [Erratum to document cited in CA117(15):146817c]

Debono, Manuel, Molloy, R. Michael, Occolowitz, John L., Paschal, Jonathan W., Hunt, Ann W., Michel, Karl H., Martin, James W.

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 139 KB

english, 1993

24

Isolation and structure of the novel branched-chain amino sugar derived from antibiotic A35512B

Debono, Manuel, Molloy, R. Michael

Journal:

Journal of Organic Chemistry

Year:

1980

Language:

english

File:

PDF, 428 KB

english, 1980

25

Structure of antibiotic A41030A

Hunt, Ann H., Dorman, Douglas E., Debono, Manuel, Molloy, R. Michael

Journal:

Journal of Organic Chemistry

Year:

1985

Language:

english

File:

PDF, 656 KB

english, 1985

26

Structure of the pseudoaglycon of actaplanin

Hunt, Ann H., Debono, Manuel, Merkel, Kurt E., Barnhart, Mitchell

Journal:

Journal of Organic Chemistry

Year:

1984

Language:

english

File:

PDF, 710 KB

english, 1984

27

[IEEE EUROCON 2007 - The International Conference on "Computer as a Tool" - Warsaw, Poland (2007.09.9-2007.09.12)] EUROCON 2007 - The International Conference on "Computer as a Tool" - A Genetic Algorithm Approach to User Location Estimation in UMTS Networks

Magro, Manuel J., Debono, Carl J.

Year:

2007

Language:

english

File:

PDF, 648 KB

english, 2007

28

The echinocandins: antifungals targeted to the fungal cell wall

Journal:

Expert Opinion on Investigational Drugs

Year:

1994

Language:

english

File:

PDF, 830 KB

english, 1994

29

The structure of the calcium complex of A23187, a divalent cation ionophore antibiotic.

CHANEY, MICHAEL O., JONES, NOEL D., DEBONO, MANUEL

Journal:

The Journal of Antibiotics

Year:

1976

Language:

english

File:

PDF, 1.59 MB

english, 1976

30

A 35512, a complex of new antibacterial antibiotics produced by Streptomyces candidus. II. Chemical studies on A35512B.

DEBONO, MANUEL, MOLLOY, R. MICHAEL, BARNHART, MITCHELL, DORMAN, DOUGLAS E.

Journal:

The Journal of Antibiotics

Year:

1980

Language:

english

File:

PDF, 5.33 MB

english, 1980

31

Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: The synthesis and evaluation of daptomycin (LY146032).

DEBONO, MANUEL, ABBOTT, BERNARD J., MOLLOY, R. MICHAEL, FUKUDA, DAVID S., HUNT, ANN H., DAUPERT, VERONICA M., COUNTER, FREDERICK T., OTT, JOHN L., CARRELL, CLAUDE B., HOWARD, LEONARD C., BOECK, LA VER

Journal:

The Journal of Antibiotics

Year:

1988

Language:

english

File:

PDF, 833 KB

english, 1988

32

Deacylation of A21978C, an acidic lipopeptide antibiotic complex, by Actinoplanes utahensis.

BOECK, LA VERNE D., FUKUDA, DAVID S., ABBOTT, BERNARD J., DEBONO, MANUEL

Journal:

The Journal of Antibiotics

Year:

1988

Language:

english

File:

PDF, 438 KB

english, 1988

33

Synthesis and antimicrobial evaluation of 20-deoxo-20(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives.

DEBONO, MANUEL, WILLARD, KEVIN E., KIRST, HERBERT A., WIND, JULIE A., CROUSE, GARY D., TAO, EDDIE V., VICENZI, JEFFREY T., COUNTER, FRED T., OTT, JOHN L., OSE, EARL E., OMURA, SATOSHI

Journal:

The Journal of Antibiotics

Year:

1989

Language:

english

File:

PDF, 903 KB

english, 1989

34

Deacylation of echinocandin B by Actinoplanes utahensis.

BOECK, LA VERNE D., FUKUDA, DAVID S., ABBOTT, BERNARD J., DEBONO, MANUEL

Journal:

The Journal of Antibiotics

Year:

1989

Language:

english

File:

PDF, 401 KB

english, 1989

35

ChemInform Abstract: E.T.H.-SERIEN UEBER PHOTOCHEMISCHE RK. 57. MITT. PHOTOLYSE VON 9ALPHA,10ALPHA- UND 9BETA,10BETA-OXIDOOESTREN-(4)-ONEN-(3)

DEBONO, MANUEL, MOLLOY, R. MICHAEL, BAUER, DANIEL, IIZUKA, TAKESHI, SCHAFFNER, KURT, JEGER, OSKAR

Journal:

Chemischer Informationsdienst. Organische Chemie

Year:

1970

File:

PDF, 157 KB

1970

36

[IEEE 2018 IEEE International Conference on Imaging Systems and Techniques (IST) - Krakow, Poland (2018.10.16-2018.10.18)] 2018 IEEE International Conference on Imaging Systems and Techniques (IST) - A comprehensive virtual reality system for tunnel surface documentation and structural health monitoring

Attard, Leanne, Debono, Carl James, Valentino, Gianluca, di Castro, Mario, Osborne, John Andrew, Scibile, Luigi, Ferre, Manuel

Year:

2018

Language:

english

File:

PDF, 214 KB

english, 2018

37

Review: Anti-infectives Echinocandin lipopeptide antifungal agents: New agents and recent chemical modification studies

Journal:

Expert Opinion on Therapeutic Patents

Year:

1995

File:

PDF, 1.48 MB

1995

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